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CRL-40,940 (Flmodafinil) Vs Modafinil Dab tsi yog qhov sib txawv ntawm 1
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CRL-40,940 (Flmodafinil) Vs Modafinil: Dab tsi yog qhov sib txawv?

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1. CRL-40,940 (Flmodafinil) Vs Modafinil: Txoj kev xaus
2. CRL-40,940 (Flmodafinil) Vs Modafinil: Mechanism of Action
3. CRL-40,940 (Flmodafinil) Vs Modafinil: Cov kev pab cuam
4. CRL-40,940 (Flmodafinil) Vs Modafinil: Dosage
5. CRL-40,940 (Flmodafinil) Vs Modafinil: Lwm Qhov Teebmeem
6. CRL-40,940 (Flmodafinil) Vs Modafinil: Legality
7. CRL-40,940 (Flmodafinil) Vs Modafinil: Yuav ua li cas muas
8. CRL-40,940 (Flmodafinil) Vs Modafinil: Txheej txheem cej luam

Los ntawm cov chaw kuaj mob rau lub lag luam ua lag luam, ob qho tib si flmodafinil thiab modafinil ua pov thawj los ua kom muaj txiaj ntsig zoo dua rau kev txhawb nqa lub peev xwm. Yog cov neeg ua hauj lwm txhawb zog, qhov kev pabcuam yuav pab koj tus ace los ntawm kev ua haujlwm hauv daim kab xev.

Tsis nco qab txog IQ los yog tsis txawj ntse txawj ntse! Ntse tshuaj tau tag nrho cov kev npau taws rau luag txog peb lub xyoo tam sim no.

Kuv paub tias koj muaj peev xwm nug tias vim li cas koj yuav tsum tau tawm ntawm lub cua ntswj thaum koj tuaj yeem them nyiaj rau ib qho amphetamine. Zoo, qhov tsab xov xwm no yuav qhia rau koj txog kev txiav txim siab seb puas yuav khom rau ib qho tshuaj yeeb los yog txiav txim siab txog hom caffeine li niaj zaus, uas yuav tsis co koj tus account hauv txhab nyiaj.

Ua ntej kuv delve rau hauv cov lus, koj yuav tsum to taub tias peb cov nootropics tsuas yog rouse lub hauv paus mob hlwb. Txawm li cas los xij, lwm txoj kev kub hnyiab tuaj tua hluav taws. Qhov no yog ib feem ntawm qhov laj thawj uas yog vim li cas amphetamines thiab caffeinated drinks ignite cov tsos mob tseem ceeb xws li kev ntxhov siab, zoo siab, thiab qaug zog.

So, how do vs modafinil reviews compare? Let’s find out.

1. CRL-40,940 (Flmodafinil) Vs Modafinil: Txoj kev xaus Piv txwv

Ob qho tib si flmodafinil thiab modafinil yog cov nootropics ntsig txog kev mus rau kev mob nkeeg, adrafinil, thiab fladrafinil. Peb tau siv lawv cov keeb kwm rov qab rau 1986, thaum lub tuam txhab ua pioneer, Laboratoire Lafon, xa daim ntawv thov patent hauv Fabkis. Adrafinil yog ib lub qauv rau ob tug eugeroics.

Cov kws soj ntsuam Lafon coincidentally sab modafinil hmoov hauv 1976 raws li lawv tau saib rau hauv adrafinil. Los ntawm 1994, lub tuam txhab tso tawm lub compound nyob rau hauv kev ua lag luam raws li Fabkis cai tau pom zoo ntawm nws.

Plaub lub xyoos tom qab, US Food thiab Drug Administration tau pom zoo kho tus mob hu ua narcolepsy. Dab tsi ntau, nws tau yog ib hom tshuaj siv rau cov neeg mob uas muaj kev ua hauj lwm pw tsaug zog, ua hauj lwm hnyav nruab hnub, thiab pw tsaug zog apnea.

Koj twb tsis tau hnov ​​txog flmodafinil. Qhov tshij, qhov no yog qhov tshiab eugeroic ntawm cov pab pawg neeg ntawm cov yeeb tshuaj uas tau ntaus cov headlines txij thaum 2013. Cov khoom tau tshawb nrhiav txij thaum 2015. Kev ceev ceev mus rau clinicaltrials.gov qhia tseeb tias muaj ib tus neeg tsis tu ncua mus sim tshuaj yeeb tshuaj.

Flmodafinil yog lwm tus hu ua CRL-40,940 hmoov. Txawm hais tias nws cov qauv ua muaj me ntsis zoo ib yam li modafinil, lub compound muaj ob hom tshuaj fluorine. No feature yog tsim nyog vim li cas vim flmodafinil tseem hu ua bisfluoromodafinil. Lwm cov npe muaj xws li lauflumide, bis- (p) -fluoromodafinil, thiab N-deshydroxyl fladrafinil.

Raw CRL-40,940 yog nrhiav tau nrog CAS naj npawb 90280-13-0 thaum modafinil hmoov yog tuaj ntawm 68693-11-8.

2. CRL-40,940 (Flmodafinil) Vs Modafinil: Mechanism of Action Piv txwv

Txij li thaum CRL-40,940 (90280-13-0) thiab modafinil tuaj yeem pom cov teebmeem, lawv cov kev ua haujlwm yog qhov zoo sib xws. Qhov tsuas yog qhov sib txawv yog qhov ob pawg-pawg uas tau koom hauv cov qauv flmodafinil, uas ua rau kom tsis muaj qhov tsis yog bioavailability.

Cov nootropics ua rau ntawm cov hlab ntsha qog hlwb, xws li dopamine, histamine, norepinephrine, orexin, serotonin, thiab glutamate. Tsuas yog cov tshuaj ntse tsis kam tuav lub dopamine rov qab los, tab sis tseem tuav lawv qib theem siab hauv lub hlwb. Lub cev dopaminergic yog lub luag haujlwm rau kev mob hlwb, kev vam meej, thiab kev txawj ntse.

Lub tswv yim kho ntawm kev ua haujlwm ntawm flmodafinil thiab modafinil tseem tsis meej, tshwj xeeb tshaj yog rau cov kev kho mob narcolepsy thiab pw tsaug zog. CRL-40,940 selectively inhibits dopamine reuptake nyob rau hauv cov hypothalamus. Kev ua haujlwm ntawm cov yeeb yam ntawm cov tshuaj neurotransmitters tau tshwm sim hauv kev ua siab dua, kev laus, kev paub zoo, kev paub, thiab zoo siab tuaj.

3. CRL-40,940 (Flmodafinil) Vs Modafinil: Cov kev pab cuam Piv txwv

Ob leeg CRL-40,940 flmodafinil hmoov thiab modafinil pom zoo ib yam li cov teeb meem txog kev puas hlwb. Tom qab tag nrho, tus qub yog tus derivative ntawm lwm.

Tib qho laj thawj yog vim li cas thiaj hloov tau modafinil yog kho thiab tswj cov tshuaj narcolepsy. Clinically, cov kws kho mob yuav pom zoo rau nws rau cov neeg mob uas pw tsaug zog apnea, hypersomnia, thiab cov neeg uas muaj teeb meem nrog kev ua hauj lwm pw tsaug zog. Dhau li ntawd, nws yog ib qho tshuaj rau kev siv tshuaj rau fibromyalgia thiab ntau yam sclerosis. Flmodafinil yog qhov newest version of modafinil hmoov.

Capitalists thiab sab saum toj moguls muab cov nootropics mus rau hauv kev sib tw kom txhawb lawv cov khoom lag luam tsim tawm. Lwm zaus koj xav muab tso rau qee qhov kev ua haujlwm hnyav vim muaj loo lossis tsaug zog, koj yuav tsum xav txog ob zaug. Kab laum 200mg yog qhov txaus kom koj tsaug zog thiab muaj peev xwm ua kom koj muaj peev xwm xav tau raws li koj txoj kev hloov ua haujlwm.

Yog tias koj yog ib tus tub ntxhais kawm uas muaj kev sib tw dhau los, koj tuaj yeem ntseeg tau nrog flmodafinil lossis modafinil ntau npaum li cas. Txawm li cas los xij, koj yuav tsum nco ntsoov tias FDA tau txiav txim siab tawm ntawm daim ntawv sau npe ntawm cov tshuaj stimulants.

Ob lub hlwb ntse txhawb zog lub zog thiab lub hlwb, txhawb txoj kev kub ntxhov, thiab ua haujlwm ntawm koj lub hlwb. Ntau cov kev tshawb fawb tshawb pom kuj hais tias cov lus qhia ua rau cov ua haujlwm nco txog txoj kev noj qab haus huv los ntawm kev txhawb nqa koj lub siab.

Ob qho CRL-40,940 (lauflumide) thiab modafinil muaj cov khoom neuroprotective. Ob peb cov kev tshawb fawb qhia tias ob qhov no tseem ceeb hauv kev kho mob paj hlwb. Dab tsi ntau, lawv ua raws li dopamine reuptake inhibitors li no boosting up agility, puas siab puas ntsws ua kom pom tseeb, thiab nce nyob rau hauv lub cev muaj zog. Feem ntau cov neeg siv kuj tau tshaj tawm tias cov tshuaj siv ua haujlwm ua haujlwm zoo li cov tshuaj tiv thaiv thiab ADHD tshuaj.

Li ntawd, ua flmodafinil cov kev pab cuam txawv los ntawm cov teebmeem modafinil?

Qhov tshij, dab tsi ua kom sib nrug yog qhov siab bioavailability tam sim no hauv flmodafinil. Qhov ntawm no tau ua rau cov neeg siv feem ntau xav tias cov tshuaj no yoo mov. Txawm hais tias tsis muaj kev thaub qab, qhov feem pua ​​tseem ceeb ntawm CRL-40,940 Reddit reviewers voucher rau nws ntau tshaj li qhov lawv sau lwm cov lus. Txhua tus neeg ntseeg hais tias cov tshuaj yog ib qho kev txhim kho cov qauv ntawm cov tsoos modafinil.

Kev ua haujlwm, cov tubrog rog ntawm UK, Teb Chaws Asmeskas, Is Nrias teb, thiab Fabkis raws cai siv modafinil ua lwm txoj rau qaug zog amphetamines. Cov tub rog thiab txawm tias cov astronauts muab cov tshuaj no thaum ua cov haujlwm ua haujlwm ntev uas yuav muaj kev txi lawv.


CRL-40,940 (Flmodafinil) Vs Modafinil Dab tsi yog qhov txawv

4. CRL-40,940 (Flmodafinil) Vs Modafinil: Dosage Piv txwv

Ob yam flmodafinil thiab modafinil muaj nyob rau hauv tshuaj ntsiav, hmoov, thiab ntsiav tshuaj los yog ntsiav tshuaj. Vim yog lub tebchaw 'siab loj, koj tuaj yeem yooj yim yaj hauv dej los yog lwm yam hnyav.

Ib tug raug modafinil noj tshuaj qhov nruab nrab ntawm 100mg thiab 200mg txhua hnub. Lub koob tshuaj hinges ntawm tus neeg siv lub siab ntev, kev noj qab haus huv, thiab lub cev qhov hnyav. Qee cov neeg siv ntxim nyiam yuav ua rau 400mg. Thaum kuv schemed los ntawm cov modafinil reddit xyuas, Kuv puzzled tawm tias feem ntau cov neeg siv ncaws tawm nrog 50mg rau 200mg.

Flmodafinil noj tshuaj lus dag ntawm 50mg thiab 100mg txawm tias qee tus neeg ntev ntev rau 200mg. Vim hais tias cov tshuaj bioavailability yog siab tshaj qhov ntawm modafinil, ntau ntawm nws yog absorbed rau hauv kev. Yog li, cov tshuaj siv qis dua qis dua lwm cov neeg laus.

Kuv xav noj cov tshuaj ntse ib zaug ib hnub, dua li thaum sawv ntxov. Koj yeej tsis xav kom cuam tshuam nrog koj lub voj voog circadian. Xyuas kom ua raws li cov lus pom zoo kom koj tsis txhob ua tus neeg raug mob ntawm kev phom sij.

Rau cov tshuaj hu ua modafinil, lub sij hawm pib yog ob xuab moos. Lub plasma concentration ntawm cov tshuaj yog nyob rau hauv nws siab tshaj plaws nyob rau hauv 6 teev thiab dauv tsis pub dhau ob xuab moos. Tom qab siv no nootropic, koj yuav nyob agile txog 12 rau 15 teev ua ntej koj tuaj yeem pib tsaug zog.

CRL-40,940 kicks hauv tsawg tshaj ib teev thiab peaks ntawm peb mus rau 6 xuab moos. Ib tug raug flmodafinil ntsiav tshuaj muaj luv luv ib nrab hnub. Yog li, koj lub voj voog yuav so tsis tu ncua. Ib tug neeg tau lees paub tias nws tseem tuaj yeem tawm ntawm 6 teev tom qab kev tswj CRL-40,940. Contrary, ntawm modafinil, nws coj nws ib 12-teev ua ntej nws yuav ntes tau pw.

5. CRL-40,940 (Flmodafinil) Vs Modafinil: Lwm Qhov Teebmeem Piv txwv

Yog hais tias koj mus los ntawm cov txheeb xyuas hauv online forums, koj yuav pom tias cov neeg siv CRL-40,940 tshaj modafinil vim tias cov tshuaj phiv flmodafinil yog ob peb. Txawm li cas los xij, cov no yog cov kev soj ntsuam ntawm mere txij thaum cov ntsiab lus ntawm 2015 theem kuv tib neeg txoj kev kawm tsis tau tawm.

Raug flmodafinil thiab modafinil phom yog cov teebmeem, mob taub hau, xeev siab, lub plawv dhia tsis sib haum, thiab kev tsis haum ntawm tawv nqaij. Koj muaj feem yuav muaj kev phom sij ntxiv yog tias koj txhaj koob tshuaj tiv thaiv kab mob siab tshaj plaws ntawm nootropics.

Nyob rau hauv rooj plaub koj tsis noj cov tshuaj Modafinil los yog flmodafinil sublingual lub sij hawm, koj mam li txhawb zog nrog insomnia. Piv txwv li, kev muab cov modafinil tom qab thaum tav su yuav muaj kev cuam tshuam rau koj tus qauv pw hauv koj lub cev. Tej zaum koj yuav nyob twj ywm kom txog thaum ib tag hmo.

Txawm li cas los xij, flmodafinil psychonauts extol CRL-40,940 vim nws luv luv ib nrab-lub neej uas tso cai rau cov neeg siv cov tshuaj zoo tom qab hnub ntawd.

Dhau li ntawm tus neeg mob txoj kev noj qab haus huv thiab kev kam rau siab, lwm cov tshuaj kuj tseem tuaj yeem tsom tau qee yam tsis zoo. Noj, piv txwv li, modafinil kev sib tshuam nrog hormonal contraceptives yuav txo qhov kev siv ntawm cov kev npaj rau tsev neeg no. Dab tsi ntxiv, cov ncauj lus yuav txo qhov kev ua si ntawm cyclosporine, Sandimmune, thiab Theophylline.

6. CRL-40,940 (Flmodafinil) Vs Modafinil: Legality Piv txwv

Feem ntau ntawm cov xeev xav kom koj muaj ib daim ntawv kho mob uas siv tau rau koj los yuav cov khoom siv modafinil. Vim cov ntaub ntawv tsis txaus, CRL-40,940 tsis muaj cov kev txwv hauv qee lub tebchaws. Feem ntau cov eBay cov neeg muag khoom tsuas yog muag cov nqaij nyoos rau kev tshawb nrhiav thiab kev kawm.

Ntawm cov prevailing modafinil cov lus ceeb toom, tiv yog ib tug ntawm lawv. Vim li no, Tebchaws Asmeskas tau muab nws tso raws li lub sijhawm IV.

Hauv Teb Chaws Asmeskas, piv txwv li, FDA tau txwv tsis pub cov chaw muag tshuaj los ntawm kev lag luam tawm rau kev lag luam tawm. CRL-40,940 tsis tau koom hauv Tebchaws Meskas thiab Canada, tabsis nws yog tshuaj noj nyob hauv Europe. Yog li, yog hais tias koj twb yog ib tug nyob sab Europe flmodafinil psychonaut, nco ntsoov tias txoj cai yog ntawm koj lub caj dab.

Lwm lub teb chaws uas tau muab cais ua piv txwv txog kev haus luam yeeb xws li teb chaws Suav, Russia, UK, Nyiv, thiab Australia. Rau cov xeev no, qhov kev siv cov tshuaj ntse ntse yog cov txwv tsis pub hnav, thiab nws yuav raug ntes nyob rau hauv Ciam Tswj Teebmeem. Txawm li cas los xij, yog tias koj nyob rau ntawm ib lub tshuaj, koj tuaj yeem taug kev ncig thaj tsam dawb.

Hauv kev ua kis las thiab kev ua kislas, lub koom haum tiv thaiv World Doping Agency (WADA) tau txwv kev siv modafinil txij thaum 2004.

7. CRL-40,940 (Flmodafinil) Vs Modafinil: Yuav ua li cas muas Piv txwv

Koj tuaj yeem tau cov no ob lub nootropics yog hauv zos lossis hauv khw muag khoom hauv online. Vim tias modafinil muas yog tsis raug cai hauv txhua lub teb chaws, koj yuav tsum tau tus kws kho mob cov tshuaj. Yog li, koj yuav tsum muaj lub laj thawj tsim nyog muab koj tus kws muag tshuaj rau lawv kom pom zoo rau cov tshuaj no.

Ib qho teeb meem ntawm lub zos muas flmodafinil lossis modafinil yog tias koj yuav tsis pom lawv nyob hauv lub tsev muag tshuaj. Yog tias koj ua, thov tuaj yeem npaj rau kev rhuav tshem lub txhab nyiaj.

Qhov tseeb flmodafinil qhov chaw yog los ntawm cov neeg muag khoom hauv online. Cia kuv piav.

Virtual sellers tsis tshua xav tau cov tshuaj. Qee qhov ntawm cov khw muag khoom muaj nyob rau hauv cov teb chaws uas cov khoos kas modafinil thiab flmodafinil yuav muaj cov kev cai noj tshuaj. Tshaj tawm, koj tuaj yeem xaiv yuav cov generic versions ntawm cov ntse cov yeeb tshuaj ntawm tus txiav nqi ntau tshaj qhov nrov nrov lub npe xaiv.

Zoo, yog tias koj xav tau cov khoom lag luam zoo heev, kos nrog peb. Peb muab cov ncauj lus kom ntxaws txog txhua yam ntawm peb cov khoom kom koj thiaj li luj cov kev txaus ntshai tshaj cov txiaj ntsig ntawm kev siv. Dab tsi ntxiv, koj tuaj yeem tso nyiaj rau peb cov kev pabcuam thiab pabcuam rau siab vim peb tsim peb cov compounds nrog tshaj 98% purity nrog HPLC kuaj.

Nkag mus rau peb lub vev xaib thiab revel hauv peb cov nqi pheej yig. Daim ntaub nplua hmoov tseem ceeb heev rau kev tshawb fawb, thaum cov tshuaj modafinil los yog flmodafinil yog rau kev siv tshuaj kho mob.

8. CRL-40,940 (Flmodafinil) Vs Modafinil: Txheej txheem cej luam Piv txwv

Ob qho CRL-40,940 thiab modafinil yog cov kev kho mob zoo tshaj plaws. Feem ntau cov rooj sab laj sawv ntsug rau lub siab bioavailability ntawm flmodafinil. Txawm li cas los xij, tsis muaj kev kawm tshawb fawb los sis tshawb xyuas kev soj ntsuam tau txhawb nqa cov teeb meem zoo flmodafinil. Dhau li ntawm, lub tuam txhab ua lag luam tau hais txog qhov kev vam meej los yog tsis ua hauj lwm ntawm theem I ntawm tib neeg kev sib tw.

Dhau li ntawm kev muaj peev xwm, qhov zoo ntawm qhov kawg CRL-40,940 thiab modafinil tshaj amphetamines yog tias lawv tsis ua rau kom muaj cov tsos mob tawm. Qhov kev tiv thaiv no tsawg dua thiab yuav luag tag nrho. Txawm li cas los xij, FDA siv qhov kev tiv thaiv no tiv thaiv modafinil thiab txwv cov koob tshuaj kom tsuas 50 ib lub tsev.

Rau bioavailability, flmodafinil yog peb champ. Nws yog yoo mov, yog li, yuav muab tshem tawm ntawm lub cev hauv lub sijhawm rau koj lub voj voog circadian. Tsis zoo li modafinil, uas nws ib nrab-lub neej txuas mus rau 14 cov sij hawm, flmodafinil yog tawm los ntawm lub cev los ntawm lub yim teev.

Qhov twg yog qhov koj xav tau ntawm ob qhov no? Qhov tshij, Kuv xav tau daim voucher rau modafinil vim nws coj lub FDA qhov kev pom zoo ua ib yam tshuaj kws kho mob tshuaj. Tsis zoo li flmodafinil, uas tsis muaj kev tshawb thiab tib neeg kawm rov qab, modafinil muaj dav-paub kho kev siv. Vim li cas thiaj yuav muaj kev pheej hmoo nrog CRL-40,940 thaum koj tseem tseem revel nyob rau hauv cov teeb meem zoo modafinil?

References

  1. Penaloza, RA Sarkar, U., Claman, DM, thiab Omachi, TA (2013). Hloov hauv Cov Ntawv Sau Npe thiab Tshawb Xo-Ntawv Modafinil Siv Hauv Tebchaws Sawv Cev Sawv Cev. JAMA Internal tshuaj.
  2. Mereu, M., Bonci, A., Newman, AH, thiab Tanda, G. (2013). Lub Neurobiology ntawm Modafinil yog ib qho Kev Cobphum ntawm Kev Ntsuas Ua Tau thiab Ib Yam Kev Kho Mob Rau Cov Khoom Uas Siv Tshuaj.
  3. Ballas, CA, Kim, D., Baldassano, CF, thiab Hoeh, N. (2002). Modafinil: Yav tag los, Tam sim no, thiab yav tom ntej.Kws Tshaj Tawm Txog Kev Kho Mob Neurotherapeutics.
  4. Eric Konofal. (2013). Patent US 20130295196 A1 - Lauflumide thiab Enantiomers Thereof, Txoj Kev Siv Npaj Tib thiab Siv Tshuaj Thoob Ntoo.
  5. Gerrad, P., thiab Malcolm, R. (2007). Mechanisms ntawm Modafinil: Kev Tshawb Fawb Txog Kev Tshawb Fawb Tam Sim No. Neuropsychiatric Disease and Treatment.

Shangke Tshuaj yog ib lub tuam txhab muaj kev lag luam siab tshwj xeeb hauv cov kws tshuaj (Intermediates) (APIs). Los tswj cov khoom kom zoo thaum lub caij ntau lawm, ntau cov kws ua haujlwm tshaj lij, cov khoom siv rau thawj qib thiab cov chaw soj ntsuam yog cov ntsiab lus tseem ceeb.

Tiv tauj peb