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Raw Nicotinamide Mononucleotide (NMN) hmoov (1094-61-7)

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Raw Nicotinamide Mononucleotide (NMN) hmoov suppressed muaj hnub nyoog lub cev hnyav nce hlwb ......


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Raw Nicotinamide Mononucleotide (NMN) hmoov (1094-61-7) video

Raw Nicotinamide Mononucleotide (NMN) Hmoov (1094-61-7) Nqe lus piav qhia

Raw Nicotinamide Mononucleotide hmoov ("NMN" thiab "β-NMN") yog ib tug nucleotide muab los ntawm kab los thiab nicotinamide. Zoo li nicotinamide riboside, NMN yog ib hom tshuaj niacin, thiab tib neeg muaj enzymes uas siv tau NMN los ua cov nicotinamide adenine dinucleotide (NADH).

Vim hais tias NADH yog tus cofactor rau cov txheej txheem hauv mitochondria, rau sirtuins, thiab rau PARP, NMN tau kawm txog cov tsiaj qauv ua ib tus neeg tuaj yeem rau cov laus thiab cov laus. Cov tuam txhab ntxiv kev noj haus muaj aggressively marketed NMN cov khoom siv cov kev pab cuam, tab sis yog tsis muaj kev tshawb fawb tshawb rau tib neeg luam tawm tsis tau.

Raw Nicotinamide Mononucleotide (NMN) Hmoov (1094-61-7) Specifications

khoom npe Raw Nicotinamide Mononucleotide (NMN) hmoov
Tshuaj Npe Tshuaj Beta-nicotinamide ribose monophosphate; Raw Nicotinamide Mononucleotide hmoov; AC1Q6RVF; AC1L23AN; NMN (+); SCHEMBL6858129
Hom NAme Mirailabo
Chav Kawm Tshuaj Kev noj haus ntxiv
CAS Number 1094-61-7
Hauv Chikey DAYLJWODMCOQEW-TURQNECASA-N
molecular Formula C11H15N2O8P
molecular Wyim 334.22
Monoisotopic pawg 335.229 g / mol
Melting Point > 96 ° C
Freezing Point Tsis muaj hnub muaj
Loj Ib Nrab Ntawm Ib Leeg Yog li, raws li hauv daim duab 3, daim nicotinamide zoo los ntawm cov ntshav nrog ib nrab hnub ntawm 5.3 teev, whereas ib nrab ntawm lub neej ntawm nicotinic acid yog 1.1 teev.
xim Dawb rau hmoov zoo dawb
Solubility Methanol (Tsawg), Dej (Tsawg)
Snkauj Thuab cua Hygroscopic, -20˚C Lub Freezer, Nyob Hauv Kev Tshwm Sim
Application Txhawm rau ua si lub luag haujlwm ntawm lub neej thiab kev kho mob ntshav qab zib

Raw Nicotinamide Mononucleotide (NMN) hmoov (1094-61-7) Qhia

Raw Nicotinamide Mononucleotide hmoov ("NMN" thiab "β-NMN") yog ib tug nucleotide muab los ntawm kab los thiab nicotinamide. Zoo li nicotinamide riboside, NMN yog ib hom tshuaj niacin, thiab tib neeg muaj enzymes uas siv tau NMN los ua cov nicotinamide adenine dinucleotide (NADH).

Cov kev tshawb fawb tshiab qhia tias NMN yuav rov qab kho cov cellular metabolism, thiab muaj cov teebmeem los tiv thaiv kev laus. Ua tshwm sim hauv lub cev, NMN (β-Nicotinamide mononucleotide) yog qhov tseem ceeb rau kev hloov siab los ntawm kev muab cov khoom noj rau hauv lub zog. Kev txhawb NMN ua ib feem ntawm koj qhov kev ua haujlwm txhua hnub tuaj yeem muab kev txhawb zog rau lub zog, kev tiv thaiv los ntawm txoj kev laus, thiab kev pheej hmoo ntawm kev mob plawv. NMN yog tus cofactor hauv redox tshua, qhov txheej txheem tseem ceeb rau metabolic muaj nuj nqi hauv lub tsim ntawm ATP lub siab-lub zog muab cov khoom muaj nqi. NMN muaj Sirtuin activating compound uas txhawb nqa metabolic precision thiab longevity.

Kev siv ntawm Nicotinamide Mononucleotide (NMN) hmoov (1094-61-7)

  1. Nicotinamide mononucleotide nyob rau hauv tib neeg lub hlwb ua lub luag haujlwm tseem ceeb hauv kev tsim lub zog, nws muaj kev koom tes hauv cov pob txuam NAD (nicotinamide adenine dinucleotide, cell hloov tshiab coenzyme) synthesis, siv los tiv thaiv kev laus, poob ntshav qab zib thiab lwm cov khoom kho mob.
  2. Nicotinamide Mononucleotide yog cov dej-soluble vitamin, Cov khoom yog dawb crystalline hmoov, tsw ntxhiab los yog ze li ntawm odorless, ntsim hauv saj, dawb do soluble dej los yog ethanol, dissolvable nyob glycerin.
  3. Nicotinamide Mononucleotidepowderis yooj yim los nqus qhov ncauj, thiab tuaj yeem faib rau hauv lub cev, cov metabolites lossis prototype ntau tawm ntawm cov zis. Nicotinamide yog ib feem ntawm coenzyme I thiab coenzyme II plays lub luag hauj lwm ntawm hydrogen nyob rau hauv biological oxidation respiratory saw, yuav txhawb kev lom oxidation thiab cov metabolism hauv nqaij daim tawv, tswj qhov qub ntaub so ntswg (tshwj xeeb tshaj yog cov tawv nqaij, plab hnyuv loj thiab lub paj hlwb) kev ntseeg muaj lub luag haujlwm tseem ceeb.

Tsis tas li ntawd, nicotinamide muaj kev tiv thaiv thiab kev kho mob plawv, kev ua haujlwm ntawm qhov ntswg thiab kev kho mob sai sai, nicotinamide tuaj yeem txhim kho lub plawv dhia thiab atrioventricular block los ntawm verapamil.

cov kev pab cuam ntawm Nicotinamide Mononucleotide (NMN) hmoov (1094-61-7)

  • NMN Tso Zog Cov Zog Metabolism - NAD + yuav pab cuam dlhau cov zaub mov xws li suab thaj rau lub zog.
  • Txhawb Nqa Kev Noj Qab Nyob Zoo thiab Kev Hlwb.
  • Kev Txhim Kho Cov Kev Txhim Kho Cov Nadir - NAD + siv los kho kho DNA cov ntshav.
  • SIRTUIN Activator - NAD + yuav tsum tau txhaj rau peb lub neej thiav mus ua haujlwm.
  • NMN yog lub compound uas siv los ntawm Harvard Zaum los thim qee cov cim qhia ntawm kev laus cov ntaub so ntswg hauv cov nas uas pib txoj kev mus rau NAD tshuaj.
  • Kev kho NMN tiv thaiv tawm tsam raug mob CICH vim raug mob hlwb
  • NMN Kev Kho Mob Ceev taus kev puas hlwb
  • Nicotinamide mononucleotide inhibits JNK ua kom rov qab kho kab mob Alzheimer
  • NMN yuav rov qab kawm cognition hauv AD qauv nas

Pom zoo Nicotinamide Mononucleotide (NMN) hmoov (1094-61-7) Feem ntau

Qhov nquag siv cov tshuaj Nicotinamide Mononucleotide yog nyob qhov twg ntawm 250 - 1500 mg ib hnub twg.

NMN yog absorbed sai heev thiab muaj ib nrab hnub luv luv, yog li kom NAD + qib siab rau ntau npaum li cas ntawm hnub tau li nws tau pom zoo kom noj ib 125 mg capsule ntawm waking thiab lwm yav tav su yog tias noj 250 mg ib hnub twg.

Sab los ntawm Nicotinamide Mononucleotide (NMN) hmoov (1094-61-7)

Thaum Nicotinamide mononucleotide (NMN) hmoov yog ib qho tshiab ntxiv thiab kev tshawb fawb tseem tab tom, kev tshawb fawb ua kom deb li tau qhia tias nws muaj kev nyab xeeb thiab tsis muaj kuab lom.

Cov kev mob tshwm sim tsawg tsawg, tab sis khaus, kiv taub hau, tawm hws, thiab xeev siab tau raug qhia tawm qee zaus.


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References & cov khoom citations

2019 Tseeb Cov Tshuaj Yeeb Tshuaj Lawm: Nicotinamide Mononucleotide (NMN)

References

  1. Mills, KF, Yoshino, J., Yoshida, S., thiab al. (2016). Kev Tswj Ntev Lawm ntawm Nicotinamide Mononucleotide Mitigates Age-Associated Physiological Decline hauv nas. Cell Cov Metabolism.
  2. Yoshino, J., Mills, KF, Imai, SI, thiab Yoon, MJ (2011). Nicotinamide Mononucleotide, ib qho tseem ceeb NAD + Intermediate, Kho cov Pathophysiology ntawm Kev Noj Qab Haus Huv Noj-thiab Cov Ntshav Qab Zib Mob Ntshav Qab hauv Nas. Cell Cov Metabolism.
  3. Yamamoto, T., Byun, J., Zhai P., Ikeda, Y., Oka, S., thiab Sadoshima, J. (2014). Nicotinamide Mononucleotide, tus Intermediate ntawm NAD + Synthesis, Tivthaiv lub plawv los ntawm Ischemia thiab Reperfusion.
  4. Sinclair, DA, Uddin, GM, Youngson, NA, thiab Morris, MJ (2016). Lub taub hau rau Kev Tshuaj Tiv Thaiv Cov Sijhawm Ntu nrog NAD + precursor Nicotinamide Mononucleotide (NMN) thiab rau lub Limtiam ntawm Kev Qoj Ib Ce Tes Ntxhais Txiv Neej.
  5. Imai, S., Yoshino, J., Mills, KF, Grozio, A., li al. (2019) Slc12a8 yog Nicotinamide Mononucleotide Transporter. Xwm Metabolism.
  6. Lub Picciotto, NE, Mills, KF, Imai, S., Gano, LB, li al. (2016). Nicotinamide Mononucleotide Reverses Vascular Qog thiab Oxidative Kev Ntxhov nrog cov laus cov nas.
  7. Yao, Z., Gao, Z., Yang, W., thiab Jia, P. (2017). Nicotinamide Mononucleotide Inhibits JNK Activation rau Reverse Alzheimer Disease.
  8. Hou, Y., Wang, Y., Zhang, Y., Lautrup, S., li al. (2018). NAD + Supplementation Normalizes Qhov Tseem Ceeb Alzheimer Tus Ntaus thiab DNA Puas Tsam Xeem hauv tus qauv AD Nas tshiab nrog Cov Tswv Yim Kho Kho Mob Hlwb.

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