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Raw RAD140 hmoov (1182367-47-0)

nyob 5.00 tawm ntawm 5 raws li nyob rau hauv 1 neeg ntsuam xyuas
(1 neeg saib xyuas)

RAD140 hmoov yog pom tias nws yog ib qho ntawm cov tsev zoo tshaj plaws SARMs nws txoj sia. Qhov zoo tshaj plaws txog SARMS yog tias ......


raws li txoj cai: Hauv Pawg Ntau Lawm
Chav: 25kg / Nruas
Peev Xwm: 1350kg / hli

Hauj lwm

Raw RADXYUMX hmoov (140-1182367-47) video

Raw RAD140 hmoov (1182367-47-0) Hauj lwm

Raw RAD140 hmoov kuj hu ua Testolone (Raw RAD140 hmoov), nws yog ib qho kev xaiv thiab androgen receptor modulator (SARM) yog tsim los ntawm lub tuam txhab kws kho mob Radius rau kev kho mob cancer ntawm lub mis thiab cov leeg khaum hauv cov poj niam postmenopausal. Testolone yog tshiab heev rau lub lag luam muag nrog nws cov thawj foundations hauv 2010.

Raw RAD140 hmoov ua tus nonsteroidal selective androgen receptor modulator (SARM). Nws stimulates androgen receptors nyob rau hauv cov pob txha thiab cov nqaij nrog ntau dua affinity tshaj hauv lub plawv plab. Raw RAD140 hmoov tau txais cov koob nrov ntawm cov khoom nruab nrog cev thiab cov kis las uas nrhiav kom mob loj tuaj.

Raw RAD140 hmoov (1182367-47-0) Specifications

khoom npe Raw RAD140 hmoov
Tshuaj Npe Tshuaj 2-Chloro-4-(((1R,2S)-1-(5-(4-cyanophenyl)-1,3,4-oxadiazol-2-yl)-2-hydroxypropyl)amino)-3-methylbenzonitrile
Hom NAme Testolone
Chav Kawm Tshuaj xim androgen reseptor modulator (SARM)
CAS Number 1182367-47-0
Hauv Chikey XMBUPPIEVAFYHO-KPZWWZAWSA-N
molecular Formula C20H16ClN5O2
molecular Wyim 393.831 g / mol
Monoisotopic pawg 393.099 g / mol
Melting Point Tsis muaj cov ntaub ntawv muaj
Freezing Point Tsis muaj cov ntaub ntawv muaj
Loj Ib Nrab Ntawm Ib Leeg Tsis muaj cov ntaub ntawv muaj
xim Dawb hmoov
solubility Dej Dej Cev 0.153 mg / mL
cia Thuab cua Khaws ntawm chav sov
Raw RAD140 hmoov Application Raw RAD140 hmoov yog ib qho kev tshawb nrhiav thiab xais phais tus kab mob (SARM) rau cov kev kho mob xws li cov leeg khib nyiab thiab mob cancer ntawm lub mis.

Raw Raw RAD140 hmoov (1182367-47-0) Nqe lus piav qhia

RAD140, kuj hu ua Testolone feem ntau hu ua SARM tshaj plaws. Nws yog tseem raug tshawb fawb los ntawm lub tuam txhab kws tshuaj hu ua Radius Health.

Selective Academy Receptor Modulators (SARMs) yog dab tsi tshaj plaws xav txog kev ruaj ntseg zoo rau kev yuam.

Dab tsi ua rau lawv thiaj li tshwj xeeb?

Zoo, Cov SARMs no yog xaiv ua txhua yam lawv ua. Los ntawm kev ruaj ntseg rau cov tub ntxhais thiab cov neeg tuaj yeem rau hauv androgen nyob rau hauv txoj kev xaiv, koj yuav tau txais kev pab cuam yam tsis tau txhawj txog cov kev mob tshwm sim.

Lub mechanisms qab cov tebchaw no txawv tshaj li nrog cov kev ua tau zoo tshaj plaws.

Cov SARMs xws li Testolone (RAD140) muaj cov kev phiv heev tsawg heev los ntawm kev tso ntshav uas yog vim li cas lawv thiaj li siv los ntawm bodybuilders.

Feem ntau cov neeg siv tau hais tias qhov kev xaiv thiab cov khoom siv roj ntsha txav hauv siab (SARM) yog qhov ze tshaj plaws rau kev yuam. Qhov no txhais tau tias koj yuav tau txais ib qho loj loj ntxiv hauv lean nqaij pawg thiab lub zog. Koj muaj peev xwm xiam qee cov roj rog qias neeg hauv tsev uas muaj qee yam, uas qee cov lus hais tsis tau.

Vim hais tias qhov SARM no muaj zog heev, koj tuaj yeem cia siab tias yuav tau ua kom tiav. Vim nws muaj kev siab khov kho nrog lub androgen receptors, qhov chaw no yog xav kom yog ib qho ntawm cov lusteb.

Muab cov khoom hauv kev xam pom, RAD140 nyoos hmoov muaj ib qho anabolic: tus androgenic piv ntawm 80: 1.

Cov teb uas muaj qhov siab sib txawv ntawm tus qauv anabolic muaj peev xwm paub tias nws yog neeg loj npaum li cas. Koj tuaj yeem muab tso rau 10lbs ntawm ntshiv nqaij thaum tshawb nrhiav txog SARM no.

Raw RAD140 hmoov (1182367-47-0) Mechanism of Action

RAD140 ua hauj lwm los ntawm kev ua kom cov xeeb ceem thiab cov kab mob nyob hauv lub cev. Nws lub hom phaj siab nyob rau hauv cov nqaij thiab cov pob txha thiab muaj tsawg los tsis muaj teebmeem rau ntawm qhov kev ua haujlwm ntawm kev ua me nyuam.

Qhov kev muaj peev xwm ntawm SARMs tsis nkag siab tsis tau. Lawv feem ntau yuav ua hauj lwm los ntawm kev xyuam xim ua cov proteins uas txawv dua li testosterone. Qhov no ua rau qee yam tshuaj Androgen receptors-tsuas yog hauv cov nqaij ntshiv-tau qhib lub cev, thaum qaug lwm tus.

Tus qauv ntawm RAD140 kuj sib txawv ntawm cov qauv ntawm cov tshuaj hormones steroid zoo li testosterone. Qhov no txhais tau hais tias lub cev tsis tau hloov RAD140 nyoos hmoov rau lwm cov tshuaj hormones zoo li cov tshuaj uas yuav muaj teebmeem tsis zoo.

Qhov chaw no kuj ua rau cov nqaij ntshiv kev loj hlob los ntawm kev txhim kho cov hlwb thiab cov nqaijrog.

Raws li kev tshawb hauv cov nas, RAD140 nyoos hmoov activates receptors hauv thaj tsam ntawm lub hlwb uas raug mob. Qhov no ua rau lub teeb liab hu ua MAPK txoj hauv kev uas pab tiv thaiv cov hlwb.

cov kev pab cuam ntawm Raw RAD140 hmoov (1182367-47-0)

◆ Txhaj Nqa Mus Mus Pab Pawg

RAD140 yog nrov nyob hauv zej zog lub cev tsim kho rau nws cov leeg mob. Ntau tshaj li lwm cov SARMs, nws muaj ib txoj hauv kev ua rau kom muaj zog ntawm cov nqaij ntshiv yam tsis muaj teebmeem dab tsi ntawm cov pa roj ntsha.

Dua li ntawm qhov chaw no, cov pov thawj tshawb nrhiav qab RAD140 nyoos hmoov ntau heev.

Tam sim no, tsuas muaj ib txoj kev tshawb nrhiav tsav uas tshawb nrhiav RAD140 cov nyhuv ntawm cov leeg kev loj hlob. Nyob rau hauv txoj kev tshawb no, cov kws soj ntsuam tshawb xyuas cov tshuaj sib txawv rau hauv 9 cov liab. Lawv pom tias RAD140 tau nce ntshiv nqaij loj tom qab tsuas 28 hnub ntawm kev siv.

Kev tshawb fawb ntawm tib neeg ntawm RAD140 tsis tau ua tau. Txawm li cas los xij, ib qho kev soj ntsuam ntawm SARM hu ua Ostarine tau pom tias nws kho cov nqaij ntshiv nqaij thiab lub cev ua haujlwm hauv cov laus.

◆ Cancer Mis

RAD140 yog qhia tau hais tias cov txiaj ntsim tau zoo rau kev mob khees xaws mis.

Ib hom mob cancer mis uas hu ua androgen and estrogen receptor positive (AR / ER +) yog cov tshuaj hormones. Cov tshuaj uas cuam tshuam rau cov neeg txais kev pom zoo, xws li SARMs, tej zaum muaj peev xwm muaj peev xwm muaj peev xwm ua rau mob cancer.

Hauv kev tshawb nrhiav ntawm tes, RAD140 nyoos hmoov tsis ua kom kev loj hlob ntawm AR / ER + lub mis mob hlwb ntawm thaiv cov teebmeem ntawm cov tshuaj no.

Tshwj xeeb, RAD140 tshwm rau suppress lub ESR1 noob. Cov noob no yog lub luag hauj lwm tsim cov tshuaj estrogen. Yog tias tsis muaj cov kws kho mob txaus, cov tshuaj no yuav tsum tsis muaj zog thiab tsis muaj zog.

◆ Hlwb Zoo Siab

Androgens kuj ua lub luag haujlwm tseem ceeb tiv thaiv lub hlwb. Lawv tuaj yeem ua rau kom lub hlwb loj hlob tuaj, txhim kho kev nco, thiab txo cov amyloid beta. Amyloid beta proteins yog ntseeg tias yog lub ntsiab ntawm Alzheimer's tus kab mob.

Nyob rau hauv kev tshawb ntawm cov nas, RAD140 tiv thaiv lub hlwb tawm tsam kev raug mob los ntawm amyloid beta. Txuas ntxiv, RAD140 thiab testosterone tau sib npaug zoo ntawm kev tiv thaiv cov kab mob neurotoxins.

Interestingly, qee cov neeg siv RAD140 qhia zoo zog, tab sis tsis muaj cov kev tshawb fawb kom rov qab ua li no. Tib mus rau cov lus ceeb toom ntawm nws lub peev xwm los txhim kho kev sib deev-txawm hais tias qhov no yuav theoretically yuav khi rau nws testosterone-mimicking teebmeem.

◆ Luj Poob

Cov SARMs paub tias yuav ua rau kom cov nqaij mob thaum tseem txo lub cev rog.

Tsuas yog ib txoj kev tshawb hauv cov liab saib RAD140 cov teebmeem ntawm cov leeg thiab rog. Txawm hais tias nws nce ntshiv nqaij, cov nyhuv ntawm lub cev muaj roj yog tsis meej.

Txawm li cas los xij, txoj kev tshawb no tau pom tias RAD140 pab txhim kho roj ntau ntau. Tsis tas li ntawd, cov nqaij pob txha yooj yim dua tuaj yeem ua kom siv zog siv ntxiv los txhawb kev mob ploj.

Pom zoo rau RAD140 hmoov (1182367-47-0)

Feem ntau cov neeg siv tsis tshaj 20mg ib hnub. Nws yog SARM heev ces tsis tas yuav siv ntau tshaj li kev pom zoo.

Feem ntau hloov nrog RAD140 nyoos hmoov yuav kav txhua qhov los ntawm 6 rau 8 lub lis piam. Ntxiv dua thiab, cov kws tshawb fawb txog tej zaum yuav thawb qhov no mus rau 10 lub lis piam.

Sab los ntawm Raw RAD140 hmoov (1182367-47-0)

RAD140 yog ib yam khoom tshiab heev. Nws qhov kev nyab xeeb thiab cov kev mob tshwm sim tsis tau raug tshuaj ntsuam xyuas tsis tau.

Raws li seb cov SARMs ua hauj lwm li cas, RAD140 yuav ua rau tsawg dua cov teeb meem tsis txaus siab dua li kev kuaj mob. Uas tau hais tias, RAD140 tseem muaj peev xwm ua rau cov kev mob ntsig sib sim ntawm cov tshuaj testosterone. Cov no muaj xws li:

  • Lub hlwb khov / loj hlob ntawm cov txiv neej
  • Kev txawv txav ntawm lub cev plaub hau ntawm cov poj niam
  • Hloov kev sib deev
  • Tus qauv pojniam / plaub hau poob
  • Kev hnov ​​voj voog thiab ntxhov siab / kev nyuaj siab
  • Xeev thiab ntuav

Cov cev nqaij daim tawv feem ntau ceeb toom cov plaub hau tsis zoo li ib sab nyhuv, uas yog ntxeev thaum lawv nres noj RAD140.


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References & cov khoom citations

RAD140 (Testolone): Tshawb nrhiav & Siv & Txaus ntshai

References

  1. Pier Giorgio Righetti; '' Capillary Electrophoresis hauv Analytical Biotechnology: Qhov Tshuav Ntawm Cov Kev Ntsuas ''
  2. John J. Qu, Wei Gao, Menas Kafatos, Robert E. Murphy, Vincent V. Salomonson; '' Lub Ntiaj Teb Science Suab Qeb Nruab Nruab Kev Txuas Lus: Vol.1: Science thiab Instruments ''
  3. Los ntawm American Association rau Cancer Research; '' AACR 2017 zaug: Abstracts 3063-5947 ''

1 xyuas rau Raw RAD140 hmoov (1182367-47-0)

  1. nyob 5 tawm ntawm 5

    Phcoker -

    Tau RAD140 hmoov mus ntsuam xyuas, kuaj tau pom zoo heev thiab purity!

Ntxiv ib tug saib xyuas

Koj email chaw nyob yuav tsis tsum luam tawm. Yuav tsum tau teb cov cim *

Shangke Tshuaj yog ib lub tuam txhab muaj kev lag luam siab tshwj xeeb hauv cov kws tshuaj (Intermediates) (APIs). Los tswj cov khoom kom zoo thaum lub caij ntau lawm, ntau cov kws ua haujlwm tshaj lij, cov khoom siv rau thawj qib thiab cov chaw soj ntsuam yog cov ntsiab lus tseem ceeb.

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