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Raw Cetilistat hmoov (282526-98-1)

nyob 5.00 tawm ntawm 5 raws li nyob rau hauv 1 neeg ntsuam xyuas
(1 neeg saib xyuas)

Cetilistat hmoov yog ib tug tshiab inhibitor ntawm pancreatic lipase yog tsim los ntawm Alizyme rau cov kev kho mob rog thiab txuam co-morbidities ... ..


raws li txoj cai: Hauv Pawg Ntau Lawm
Chav: 25kg / Nruas
Peev Xwm: 1410kg / hli

Hauj lwm

Raw Cetilistat hmoov (282526-98-1) video

Raw Cetilistat hmoov (282526-98-1) Nqe lus piav qhia

Raw Cetilistat hmoov yog ib tug tshiab pancreatic lipase inhibitor tsim los ntawm Alizyme rau cov kev kho mob rog thiab ntshav qab zib thiab lwm yam kab mob. Nws ua los ntawm inhibiting pancreatic lipase, ib qho enzyme uas lov nram triglycerides hauv plab. Tiv thaiv roj (triglycerides) hauv cov khoom noj los ntawm metabolized thiab hloov mus ua cov dawb fatty acids uas tau txais los ntawm lub cev. Raw Cetilistat hmoov txhawm rau txo qhov hnyav nrog thiab tau zoo dua uas tau tshaj li ntawm daim ntawv teev.

Raw Cetilistat hmoov (282526-98-1) Specifications

khoom npe Raw Cetilistat hmoov
Tshuaj Npe Tshuaj Raw Cetilistat hmoov (Alt-962); Xinliorlistat; Raw Cetilistat hmoov (282526-98-1)
Hom NAme Cametor lossis Obleej
Chav Kawm Tshuaj Cov tshuaj tiv thaiv kev rog
CAS Number 282526-98-1
Hauv Chikey MVCQKIKWYUURMU-UHFFFAOYSA-N
molecular Formula C25H39NO3
molecular Wyim 401.58
Monoisotopic pawg 401.293 g / mol
Melting Point 72.0 rau 76.0 ° C
Freezing Point 74 ° C
Loj Ib Nrab Ntawm Ib Leeg Tsis muaj hnub muaj
xim Tawm-dawb Crystal
Solubility Soluble hauv DMSO, tsis yog hauv dej
Snkauj Thuab cua -20 ° C
Application Siv los kho kev rog nrog lwm cov teebmeem

Raw Cetilistat hmoov (282526-98-1)

Cetilistat, tseem hu ua ATL-962, nws yog ib tug tshiab inhibitor ntawm pancreatic lipase yog tsim los ntawm Alizyme rau kev kho cov rog thiab kab co-morbidities, xws li hom 2 mob ntshav qab zib. Nws ua rau tib txoj kev raws li cov laus siv tshuaj yaj yeeb (Xenical) los ntawm inhibiting pancreatic lipase, ib qho enzyme uas lov nram triglycerides hauv txoj hnyuv. Yog tsis muaj qhov no enzyme, triglycerides los ntawm kev noj haus yog tiv thaiv kom tsis txhob mus ua hydrolyzed rau absorbable dawb fatty acids thiab excreted undigested. Cov tshuaj no yuav tsum tau noj nrog kev noj zaub mov kom tsis muaj roj tsawg thiab muaj ntau qhov kev qoj ib ce kom ua tau zoo tshaj plaws.

Hauv tib neeg cov kev sim, cetilistat hmoov tau pom tias yuav ua rau zoo li qhov hnyav poob rau cov ntaub ntawv, tab sis kuj ua rau cov kev mob xws li oily, cov quav hauv plab, cov quav tsis tau, kev ploj mus tsis tu ncua, thiab kev tso dag. Nws yuav hais tias tib cov kev ceev faj yuav siv rau hauv cov khoom noj uas muaj roj-soluble vitamins thiab lwm cov roj-soluble as-ham uas yuav tsum tau inhibited, ntxiv cov vitamin tshuaj siv los tiv thaiv tsis raug.

Cetilistat powr tau pom zoo los ntawm Pharmaceuticals Medical Devices Agency ntawm Nyiv (PMDA) rau lub Cuaj hlis 20, 2013. Nws tau tsim los ntawm Norgine thiab Takeda, tom qab ntawd muag raws li Oblean® los ntawm Takeda nyob rau hauv Nyij Pooj.

Cetilistat hmoov (282526-98-1) Mechanism of Action

Cetilistat hmoov yog ib lub luj pwm siv ua ke nrog noj tsawg calorie. Cetilistat yog lub plab hnyuv lipase inhibitor, nws ua haujlwm los thaiv cov roj ntau heev ntawm kev raug qias thiab nqus mus rau hauv lub cev. Qhov qog no poob phaus yog cais raws li tus lipase inhibitor thiab nws ua haujlwm ncaj qha rau lub plab zom zaws nws qhov kev txiav txim ntawm lub lipolytic enzyme hu ua lipase. Cov lipases no yog dab tsi hauv lub cev siv los zom cov rog.Txawm li cas los, thaum noj cov tshuaj no ua ke nrog ib pluas noj, nws khi rau cov lipases, li inhibiting los ntawm kev tu ncua roj. Cov rog uas tsis yog kev siv tshuaj tua kab yog siv rau hauv cov quav, uas ua rau muaj cov kab mob fecal ntau dua thiab txo cov roj tsawg. Thaum siv nrog calorie tsawg noj, nws tuaj yeem pab txhim kho qhov hnyav thiab ua kom yooj yim rau cov neeg mob rog kom rov qab tau zoo dua qub, yog li ua kom muaj peev xwm ua kom poob zoo. Nws siv txoj kev yog tib yam li cov laus los orlistat hmoov los ntawm inhibiting pancreatic lipase.

cov kev pab cuam ntawm Cetilistat hmoov (282526-98-1)

▪ Kho kev rog

Txo hauv lub cev hnyav

▪ Kho mob ntshav qab zib

▪ Zoo siab zam rau lwm yam tshuaj

Pom zoo kom kab hmoov tshuaj hmoov (282526-98-1)

Cetilistat hmoov yog muaj raws li cov ntsiav tshuaj rau kev siv lub qhov ncauj, muaj 120 mg ntawm dawb Cetilistat. Qhov kev txhaj tshuaj yog 120 mg peb zaug ib hnub twg tam sim tom qab txhua pluas noj. Cov tshuaj no yog noj nrog cov pluas noj kom paub meej tias nws tuaj yeem ua haujlwm thaum cov zaub mov raug tau nqis, kom lub cev tsis haum ntawm cov khoom noj yuav raug txo kom tsawg.

Sab los ntawm Cetilistat hmoov (282526-98-1)

Cov neeg mob niaj hnub kho rau kev rog nrog Cetilistat hmoov yuav raug kev txom nyem los ntawm kev phiv. Koj yuav tsum qhia rau koj tus kws kho mob yog tias qhov no tshwm sim. Muaj qee qhov kev phiv rau kev siv:

Rog nyob hauv cov quav

Mob plab (crampinal cramp)

Flatus nrog paug

Oily spotting

Plab hnyuv tso tawm

Kev sib cais

Mob plab

Zawv plab

Cov quav muag

Lub qhov ntswg

Nquag caij nyoog

Mob hauv plab

Xeev lossis ntuav

Kauj taub hau

Qhuav lub qhov ncauj

Tsaus muag

Tsis zoo siab lub plawv dhia

Tig los yog tsis muaj zog

Txawm hais tias me ntsis kev sib txuam yog feem ntau pom tias muaj ntau dua, cov teeb meem loj los kuj yuav tshwm sim. Nrog koj tus kws kho mob tam sim ntawd yuav tsum muaj qhov no.


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References & cov khoom citations

Vim li cas Sibutramine thiaj nrov nyob hauv kev poob phaus?

References

  • Rog: Epidemiology, Pathophysiology, thiab Kev Tiv Thaiv, Kev Sib Txuas Lus, Harry G. Preuss, nplooj 205-2012.
  • Sibutramine HCL: Rog, W. Philip James, Eleanor Bull, Ian Campbell, CSF Kev Sib Txuas Lus, 2004, phab 1-44
  • Phau Ntawv Teev Tseg: Kho Mob thiab Kev Mob, Cai Richard A. Helms, David J. Quan, Tshooj 57.

1 xyuas rau Raw Cetilistat hmoov (282526-98-1)

  1. nyob 5 tawm ntawm 5

    phcoker -

    Tau txais Raw Cetilistat hmoov mus kuaj, kuaj tau pom zoo heev thiab purity!

Ntxiv ib tug saib xyuas

Koj email chaw nyob yuav tsis tsum luam tawm. Yuav tsum tau teb cov cim *

Shangke Tshuaj yog ib lub tuam txhab muaj kev lag luam siab tshwj xeeb hauv cov kws tshuaj (Intermediates) (APIs). Los tswj cov khoom kom zoo thaum lub caij ntau lawm, ntau cov kws ua haujlwm tshaj lij, cov khoom siv rau thawj qib thiab cov chaw soj ntsuam yog cov ntsiab lus tseem ceeb.

Tiv tauj peb