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Nyoos Avanafil Hmoov (330784-47-9)

nyob 5.00 tawm ntawm 5 raws li nyob rau hauv 1 neeg ntsuam xyuas
(1 neeg saib xyuas)

Avanafil hmoov yog siv los kho cov txiv neej uas muaj erectile kawg (kuj hu ua sexual impotence). Avanafil belongs rau ib pawg ntawm ......


raws li txoj cai: Hauv Pawg Ntau Lawm
Chav: 25kg / Nruas
Peev Xwm: 1290kg / hli

Hauj lwm

Raw avanafil hmoov (330784-47-9) video

Raw Avanafil hmoov (330784-47-9) Nqe lus piav qhia

Raw Avanafil hmoov yog ib qho PDE5 inhibitor tau txais kev tso cai rau erectile kawg (ED: impotence; tsis muaj peev xwm tau los yog ua kom ib tug erection rau cov txiv neej). Nyoo Avanafil hmoov ua los ntawm inhibiting ib hom phosphodiesterase yam 5 enzyme uas muaj nyob rau hauv ntau cov ntaub so ntswg, tab sis feem ntau nyob hauv lub corpus cavernosum noov, thiab cov retina. Nws ua haujlwm los ntawm kev nce ntshav ntws mus rau chaw mos thaum lub sijhawm kev sib deev. Lwm cov yeeb tshuaj zoo li yog sildenafil, tadalafil thiab vardenafil. Qhov zoo ntawm Raw Avanafil hmoov yog tias nws muaj kev kub ceev pib ua piv nrog lwm PDE5 inhibitors. Nws yog absorbed sai sai, ncav lub siab tshaj plaws concentration nyob rau hauv 30-45 feeb.Qhov ob feem peb ntawm cov neeg koom muaj peev xwm mus koom rau hauv kev sib deev ua si tom qab 15 feeb.

Nyoos Avanafil Hmoov (330784-47-9) Specifications

khoom npe Nyoo Avanafil hmoov
Tshuaj Npe Tshuaj 330784-47-9;STENDRA; (s)-4-((3-Chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)-N-(pyrimidin-2-ylmethyl)pyrimidine-5-carboxamide; TA 1790; TA-1790
Hom NAme Stendra thiab Spedra
Chav Kawm Tshuaj PDE5 inhibitor
CAS Number 330784-47-9
Hauv Chikey WEAJZXNPAWBCOA-INIZCTEOSA-N
molecular Formula C23H26ClN7O3
molecular Wyim 483.95
Monoisotopic pawg 483.179 g / mol
Melting Point 150-152 ° C
Freezing Point Tsis muaj cov ntaub ntawv muaj
Loj Ib Nrab Ntawm Ib Leeg Txhais tau tshem tawm ib nrab neej = 5.36 - 10.66 teev
tsos Dawb hmoov
Solubility DMSO, Methanol
Snkauj Thuab cua Khw ntawm 4 ° C
Daim ntawv thov Lub phosphodiesterase (PDE5) inhibitor, siv los kho erectile kawg.

Raw Avanafil hmoov (330784-47-9) Nqe lus piav qhia

Avanafil yog siv los kho erectile kawg (ED: impotence; tsis muaj peev xwm tau los yog khaws ib qho erection rau cov txiv neej). Avanafil hmoov yog nyob rau hauv ib chav kawm ntawm cov tshuaj hu ua phosphodiesterase (PDE) inhibitors. Nws ua haujlwm los ntawm kev nce ntshav ntws mus rau chaw mos thaum lub sijhawm kev sib deev. Qhov no nce ntshav txaus yuav ua rau muaj erection. Avanafil hmoov tsis kho erectile kawg lossis kom muaj kev sib deev muaj siab. Avanafil tsis tiv thaiv kev xeeb tub los sis kis cov kab mob sib kis los ntawm kev sib deev xws li kab mob human immunodeficiency virus (HIV).

Avanafil hmoov (330784-47-9) Mechanism of Action

Avanafil yog ib qho selective phosphodiesterase 5 (PDE5) enzyme inhibitor siv rau kev kho mob erectile kawg tshwm sim los ntawm ntshav qab zib, muaj hnub nyoog vim muaj kev nyuab siab oxidative los yog lwm yam teeb meem. Avanafil inhibits tus cGMP hom phosphodiesterase hom 5 (PDE5) uas yog lub luag hauj lwm rau kev degradation ntawm cGMP hauv lub corpus cavernosum nyob ib ncig ntawm chaw mos. Penile erection thaum kev sib deev stimulation yog tshwm sim los ntawm cov pob txha rab qaum ntshav nce los ntawm kev so ntawm rab qau roj ntsha thiab corpus cavernosal tus leeg. Cov lus teb no yog kho los ntawm kev tso tawm ntawm nitric oxide (TSIS YOG) los ntawm cov hlab ntsha thiab cov hlwb endothelial, stimulates tus synthesis ntawm cGMP hauv cov leeg hlwb. Cyclic GMP ua rau cov nqaij ntshiv kom muaj zog thiab ua rau cov ntshav nce siab mus rau hauv lub corpus cavernosum. Tus inhibition of phosphodiesterase hom 5 (PDE5) los ntawm avanafil pab erectile muaj nuj nqi los ntawm kev nce tus nqi ntawm cGMP.

Daim ntawv thov Avanafil hmoov (330784-47-9)

Avanafil hmoov yog siv los kho cov txiv neej uas muaj erectile kawg (kuj hu ua sexual impotence).

Pom zoo Avanafil hmoov (330784-47-9) Dosage

Rau feem ntau ntawm cov tib neeg, qhov kev pom zoo pib koob hmoov ntawm avanafil hmoov yog 100 mg ib hnub npaum li cas txog 30 feeb ua ntej kev sib deev. Nyob ntawm seb cov lus teb los sis cov kev mob tshwm li cas, cov koob tshuaj yuav tau nce ntxiv rau 200 mg los yog txo cov tshuaj 50 ib hnub. Cov tib neeg uas noj cov tshuaj uas tsis tuaj yeem ua rau cov qib siab avanafil ntau dua yuav tsum tsis pub dhau tag nrho cov tshuaj 50 mg hauv 24 cov xuab moos (Saib cov kev sib hloov tshuaj).

Cov txiaj ntsig ntawm Avanafil hmoov (330784-47-9)

Txhob siv cov avanafil thiab hu koj tus kws kho mob ib zaug yog koj muaj:

▪ kev hloov qhov muag, kev tsis pom kev tsis pom kev;

▪ ringing hauv koj lub pob ntseg, los yog tsis hnov ​​lus zoo;

▪ mob, o, sov sov, lossis liab liab nyob rau hauv ib los yog ob qho tag nrho ob txhais ceg;

▪ ua tsis taus pa, ua rau koj txhais tes lossis taw;

▪ ib qho kev xav taws, zoo li koj yuav kis tau; los yog

▪ penis erection uas mob heev los yog kav ntev dua 4 los yog ntev dua.

Cov kev mob tshwm sim muaj xws li:

▪ mob taub hau;

▪ da dej (sov so, liab, los yog muaj kev xav);

▪ cov tsos mob khaub thuas xws li los ntswg lossis txhaws ntswg, mob caj pas; los yog

▪ mob nraub qaum.


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References & cov khoom citations

9 lus nug kom nug koj tus kheej ua ntej koj yuav tau txais Avanafil

References

  1. Ryan M Burke, Jeffery D Evans, Avanafil rau kev kho mob ntawm erectile kawg: xyuas nws cov peev xwm, Vasc Health Risk Manag. 2012; 8: 517-523.
  2. DeRogatis LR, Burnett AL. Lub epidemiology ntawm kev sib deev dysfunctions. J Kev Sib Txawv Sij Hawm. 2008; 5: 289-300.
  3. Zhao C, Kim S, Yan D, li al. Kev siv thiab kev nyab xeeb ntawm avanafil rau kho erectile kawg: tau ntawm ntau hom, randomized, muab ob npaug rau-dig muag, tshuaj ntsuam tshuaj placebo. BJU Int. 2012 Mar 27;

1 xyuas rau Nyoos Avanafil Hmoov (330784-47-9)

  1. nyob 5 tawm ntawm 5

    phcoker -

    Tau Raw Avanafil hmoov mus ntsuam xyuas, kuaj tau pom zoo heev thiab zoo!

Ntxiv ib tug saib xyuas

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Shangke Tshuaj yog ib lub tuam txhab muaj kev lag luam siab tshwj xeeb hauv cov kws tshuaj (Intermediates) (APIs). Los tswj cov khoom kom zoo thaum lub caij ntau lawm, ntau cov kws ua haujlwm tshaj lij, cov khoom siv rau thawj qib thiab cov chaw soj ntsuam yog cov ntsiab lus tseem ceeb.

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