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Raw Synephrine HCL hmoov (5985-28-4)

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Synephrine HCL hmoov yog ib qho tshwm sim los ntawm alkaloid tshuaj lom neeg muaj tshuaj nyob hauv cov nroj tsuag thiab muab siv rau ......


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Raw Synephrine HCL hmoov (5985-28-4) video

Raw Synephrine HCL hmoov (5985-28-4)

Raw Synephrine HCL hmoov yog ib qho uas tshwm sim los ntawm alkaloid tshuaj lom neeg pom muaj cov nroj tsuag thiab muab rho tawm los siv ua ntxiv. Synephrine tej zaum kuj hu ua 'iab txiv kab ntxwv' raws li nws muab los ntawm cov txiv kab ntxwv me. Hauv qhov tseeb tiag, nws yog ib txwm pom nyob rau hauv lub rind ntawm lub txiv kab ntxwv, uas yog vim li cas nws yog lub npe hu ua iab txiv kab ntxwv. Cov kua txiv kab yog tam sim no siv rau cov teeb meem zoo ib yam xws li qee qhov teeb meem niaj hnub niaj hnub xws li yuag poob thiab raws li kev pab rau kev sib ntaus sib tua tiv thaiv tus neeg ncaws pob. nws yog ib lub ntsiab lus teb nyob rau hauv iab txiv kab ntxwv thiab xav tias yuav tsum yog lub hauv paus ntawm cov nroj tsuag kev kho zoo Cov Nqaij Synephrine HCL hmoov, arguably qhov zoo tshaj roj hlawv cov khoom xyaw.Synrrine yog tau los ntawm lub txiv kab ntxwv, thiab thaum koj muaj nws, koj ua tau ces kev pab nyob rau hauv tag nrho cov thawj coj ntawm ntau txoj kev.

Raw Synephrine HCL hmoov (5985-28-4) Specifications

khoom npe Raw Synephrine HCL hmoov
Tshuaj Npe Tshuaj Synephrine hydrochloride; 5985-28-4; 4- (1-Hydroxy-2- (methylamino) ethyl) phenol, hydrochloride;
Hom NAme Yocon
Chav Kawm Tshuaj Fat poob
CAS Number 5985-28-4
Hauv Chikey COTCEGYSNTWJQV-UHFFFAOYSA-N
molecular Formula C9H14ClNO2
molecular Wyim 203.666 g / mol
Monoisotopic pawg 203.071 g / mol
Melting Point 147-150 ° C
kub Point 341.10 ° C. @ 760.00 mm Hg (yog)
Loj Ib Nrab Ntawm Ib Leeg Tsis muaj hnub muaj
xim Dawb rau hmoov zoo dawb
Solubility Tsis muaj hnub muaj
Snkauj Thuab cua tub yees
Application Arguably qhov zoo tshaj roj hlawv cov khoom xyaw

Raw Synephrine hcl hmoov (5985-28-4) Description

Raw Synephrine HCL hmoov yog ib qho uas tshwm sim los ntawm alkaloid tshuaj lom neeg pom muaj cov nroj tsuag thiab muab rho tawm los siv ua ntxiv. Synephrine tej zaum kuj hu ua 'iab txiv kab ntxwv' raws li nws muab los ntawm cov txiv kab ntxwv me. Hauv qhov tseeb tiag, nws yog ib txwm pom nyob rau hauv lub rind ntawm lub txiv kab ntxwv, uas yog vim li cas nws yog lub npe hu ua iab txiv kab ntxwv. Cov kua txiv kab yog tam sim no siv rau cov teeb meem zoo ib yam xws li qee qhov teeb meem niaj hnub niaj hnub xws li yuag poob thiab raws li kev pab rau kev sib ntaus sib tua tiv thaiv tus neeg ncaws pob. nws yog ib lub ntsiab lus teb nyob rau hauv iab txiv kab ntxwv thiab xav tias yuav tsum yog lub hauv paus ntawm cov nroj tsuag kev kho zoo Cov Nqaij Synephrine HCL hmoov, arguably qhov zoo tshaj roj hlawv cov khoom xyaw.Synrrine yog tau los ntawm lub txiv kab ntxwv, thiab thaum koj muaj nws, koj ua tau ces kev pab nyob rau hauv tag nrho cov thawj coj ntawm ntau txoj kev.

Raws li kev noj zaub mov ntxiv, synephrine HCL hmoov feem ntau yuav zoo rau feem ntau cov neeg loj hlob thaum siv kom zoo. Txawm li cas los xij, muaj qee qhov teeb meem nyhav me me ntawm cov neeg siv uas siv ntau tus synephrine hcl. Synephrine yog ib qho stimulant, yog li nws yog ib qho tseem ceeb rau kev pib ntawm ib qib qis rau kev ntsuam xyuas kam rau siab. Cov neeg mob HCL ntev li qub tuaj yeem ua rau mob ntshav nce siab, mob plawv dhia, mob plawv, ua kom tsis muaj zog, ntxhov siab, ua pa nyuab, kiv taub hau, mob taub hau, tshaib plab, tsis muaj ntshav qab zib thiab ntshav qab zib tsis sib haum xeeb, mob plab, xeev siab thiab zawv plab, tshwj xeeb nrog rau lwm cov stimulants.

Synephrine hcl hmoov (5985-28-4) Mechanism of Action

Kev mob plawv ntawm ligands yog txuam nrog adrenergic reseptor ruaj. Txuas ntxiv, thaum ligands khi rau α-adrenergic receptors, vasoconstriction tshwm sim, thiab thaum khi rau β1-adrenergic receptors, plawv contractility thiab ntxiv lub plawv dhia. Cov kev tshawb fawb qhia tau tias synephrine hcl hmoov binds rau β3-adrenergic receptors, ua rau muaj kev nce qib hauv lub cev ua kom muaj zog zom. Kev ruaj ntseg rau cov phom sij ntawm tus kab mob hu ua β3-adrenergic tsis cuam tshuam rau lub plawv dhia lossis ntshav siab. Dua li, vim hais tias synephrine tuaj yeem tsis pom los yog tsis muaj kev ruaj siab rau α1-, α2-, β1-, thiab β2-adrenergic receptors thiab tsis tuaj yeem ua kom tsis ncaj nce rau cov teebmeem, plawv teebmeem, xws li nce siab thiab ntshav siab, tsis yog kev paub siv ntau zaus, tsis zoo li ib tug xov tooj ntawm lwm cov phenylethylamine thiab phenylpropanolamine derivatives. Cov kev hloov me me ua rau cov kev sib txawv ntawm cov adrenergic reseptor ruaj thiab tom qab lub peev xwm tsim cov teebmeem plawv.

Synephrine hcl hmoov kuj ua rau lub cev siv cov carbohydrates los ua cov hluav taws xob ntau dua hauv daim ntawv ntawm ATP.49-52 Nws pab txhawb nqa kev lag luam ntawm cov qe hauv cov leeg mob hlwb, nrog rau glycogenolysis, gluconeogenesis, glycolysis, thiab cov pa oxygen. Kev koom tes ntawm ob qho tib si calcium ion thiab cAMP nrog adrenergic receptors tau pom hais tias muaj kev koom tes hauv cov txheej txheem biochemical, qhia tias kev koom tes ntawm ntau lub tswv yim.

Ntawm ib sab, kev siv cov tshuaj Synephrine hcl hmoov yuav ua rau cov neeg muaj mob NF-kB. Qhov yeeb tshuaj no yog qhov tseem ceeb hauv kev ua rau muaj kev mob nkeeg xws li hawb pob. Kev siv cov tshuaj Synephrine kuj tau pom los cuam tshuam qhov kev txiav txim ntawm lub eotaxin-1 hormone lom zem ntau. Qhov no txwv tsis pub lub zog ntawm eosinophil mus rau thaj tsam uas muaj tus mob.

Txawm hais tias tsis zoo los ntawm kev sim, kev siv cov Synephrine hcl hmoov tau pom muaj inhibit qhov kev txiav txim ntawm acetylcholinesterase. Cov tshuaj no yog paub tias ua rau Alzheimer's mob.

cov kev pab cuam ntawm Synephrine hcl hmoov (5985-28-4)

  • Synephrine hcl rau poob phaus
  • Synephrine hcl pab tsis tau txoj kev noj qab haus huv
  • Synephrine hcl nce zoo dua cov nqaij ntshiv qab zib
  • Synephrine hcl improove aids glycogenesis
  • Synephrine hcl pab tswj kev mob ntshav qab zib
  • Synephrine hcl txhim kho plab zom mov
  • Synephrine hcl txo nervousness ua ntej phais
  • Synephrine hcl txhim kho siab thiab lub zog sib luag
  • Synephrine hcl pab tswj cov kab mob teeb meem
  • Synephrine hcl pab kev txo qhov mob tsawg

Pom zoo Synephrine hcl hmoov (5985-28-4) Kev Siv Tshuaj

Qhov feem ntau uas siv cov tshuaj Synephrine hcl yog li ntawm 100mg ib hnub twg. Qhov no xam tau tias yuav tsum tau noj ntau txaus kom ua tau yuag poob. Txawm li cas los xij, qhov nyiaj kom pom zoo uas txawm tias tus neeg siv cov khoom siv yuav tsum tsis txhob tshaj yog 200mg ib hnub. Txhua yam saum toj no lub cim no yog qhov ua kom muaj mob thiab yuav ua rau tus neeg ntawd yuav muaj qhov phom sij ntawm kev phiv cov kev phom sij uas muaj feem xyuam nrog kev siv cov tshuaj stimulants. Nws yog ib qho tsim nyog, pib nrog, 10 rau 20mg kom paub tseeb tias Synephrine hcl hmoov yog sib thooj nrog koj lub cev. Tom qab noj thawj zaug no, koj yuav tsum siv sij hawm los ntsuam xyuas lub cev cov lus teb rau qhov ntxiv. Yog tias txhua yam zoo, qhov thib ob ntawm 20mg tuaj yeem raug ntxiv tom qab ob xuab moos. Nyob ntawm ib sab, qhov siv tshuaj kom tsawg tshaj plaws yog noj Synephrine hcl hmoov ib zaug txhua ob xuab moos.

Sab los ntawm Synephrine hcl hmoov (5985-28-4)

Kev siv cov tshuaj hu ua Synephrine kuj tseem nrog cov kev phiv los yog lwm yam tshuaj. Thaum twg ib zaug ob peb zaug siv cov tshuaj synephrine hcl nrog ua ke caffeine. kuj tuaj nrog qee qhov kev mob tshwm sim. Cov nram qab no yog qee cov kev phiv tshuaj:

  • Ntshav siab.
  • Kab mob hauv lub plawv.
  • Tsis zoo siab lub plawv dhia.
  • Ua rau tuag taus yog tias siv ntau npaum li ua ntej kev phais.
  • Kev hnov ​​mob / kev puas hlwb
  • Coronary spasms thiab thrombosis
  • Lub plawv atherosclerosis disturbances (qhov ntswg fibrillation)
  • Ib tug thawj txo ntawm cov leeg mob (rhabdomyolysis)
  • Lub raum tsis ua hauj lwm
  • Ntshav xaj
  • Puas tsuaj raug vim muaj kev ntxhov siab hauv cov leeg (ob sab sib luag ntawm cov quav)
  • Mob hauv siab (variant angina)
  • stroke


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References & cov khoom citations

How Synephrine HCL Ua Hauj Lwm Ntawm Koj Lub Cev Li Cas?

References

  1. Akhlaghi, M., Shabanian, G., Rafieian-Kopaei, M., Parvin, N., Saadat, M., thiab Akhlaghi, M. Citrus aurantium blossom thiab preoperative ntxhov siab. Rev Bras.Anestesiol. 2011; 61 (6): 702-712.
  2. Bent, S., Padula, A., thiab Neuhaus, J. Kev nyab xeeb thiab ua tau ntawm citrus aurantium rau qhov poob phaus. Am.J.Cardiol. 11-15-2004; 94 (10): 1359-1361
  3. Campbell-Tofte, JI, Molgaard, P., Josefsen, K., Abdallah, Z., Hansen, SH, Cornett, C., Mu, H., Richter, EA, Petersen, HW, Norregaard, JC, thiab Winther, K. Randomized thiab ob lub qhov muag pom kev soj ntsuam ntawm kev nyab xeeb thiab kev ua kom tsis muaj teeb meem ntawm cov Rauvaulia-Citrus tshuaj yej, raws li siv hauv Nigerian tshuaj. J Ethnopharmacol. 1-27-2011; 133 (2): 402-411.
  4. R. Costa, MBA Glória, hauv phau Encyclopedia ntawm Food Sciences thiab khoom noj khoom haus (Thib Ob), 2003
  5. Ghanim H, Sai CL, Upadhyay M. thiab al. Cov kua txiv kab ntxwv ua rau cov nqaij nyhav tsis muaj zog, ua rau cov zaub mov muaj roj tsawg, ua kom muaj zog thiab carbohydrate tsis zoo thiab ua rau cov kev mob zoo li tus mob hu ua Tus mob hu ua Toll-like receptor. Amer J Clin Nutr. 2010; 91: 940-949
  6. Stohs SJ. Kev soj ntsuam ntawm cov xwm txheej tshwm sim muaj feem xyuam nrog Citrus aurantium(ntsim txiv kab ntxwv) ntawm lub Plaub Hlis 2004 rau Lub Kaum Hlis 2009.
  7. Dragull K, Breksa AP, Cain B. Synephrine ntsiab lus ntawm kua txiv los ntawm Satsuma mandarins (Citrus unshiuMarcovitch). J Agric.Food Chem. 2008; 56: 8874-8878
  8. Roman MC, Betz JM, Hildreth J. Kev txiav txim siab ntawm synephrine nyob rau hauv cov ntaub ntawv raw kua txiv kab ntxwv, cov khoom noj, thiab kev noj tshuaj los ntawm kua chromatography nrog ultraviolet nrhiav kom pom: kev kuaj xyuas ib zaug xwb. J Amer Org Anal Chemists Int. 2007; 90: 68-81
  9. Mercolini L, Mandrioli R, Trere T. thiab al. Ceev ceev ntab ntawm cov adrenergic amines nyob rau ntau qhov chaw ntawm Citrus aurantiumtxiv hmab txiv ntoo thiab kev noj haus tshuaj. J Sep Sci. 2010; 32: 1-8
  10. Haaz S, Fontaine KR, Cutter G, Limdi N. thiab al. Citrus aurantiumthiab synephrine alkaloids nyob rau hauv kev kho mob rog thiab rog: kev hloov tshiab. Rog Kev Ntseeg 2006; 7: 79-88
  11. Higgins, JP, Tuttle, TD, thiab Higgins, CL Energy haus: cov ntsiab lus thiab kev nyab xeeb. Mayo Clin Proc. 2010; 85 (11): 1033-1041.
  12. Kaats, GR, Miller, H., Preuss, HG, thiab Stohs, SJ Ib 60day ob-dig muag, kev tshawb xyuas kev tshuaj placebo nrog Citrus aurantium (tshuav txiv kab ntxwv). Khoom Noj Khoom Haus Chem Toxicol. 2013; 55: 358-362.
  13. Lynch B. Txheeb xyuas kev ruaj ntseg ntawm p-synephrine thiab caffeine. Intertek-Cantox Report, 2013; 1-20.
  14. Kev soj ntsuam kev noj qab haus huv thiab cov khoom poob phaus uas muaj cov tshuaj synephrine thiab caffeine BfROpinion No. 004 / 2013, ntawm 16 Kaum Ib Hlis 2012

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